There are more than 100 different types of HPV. They differ in terms of the types of epithelium they infect. Some infect cutaneous sites, whereas others infect mucosal surfaces.Over 40 types infect mucosal surfaces, including the anogenital
epithelium (e.g., cervix, vagina, vulva, rectum, urethra, penis, and anus). For most of these HPV types, there are sufficient
data to divide them into “high-risk” (e.g., oncogenic or cancer-associated) types and “low-risk”
How Common is HPV?
Approximately 20 million Americans 15 to 49 years of age (approximately 15% of the population) are currently infected with HPV.5 Others may have been infected in the past and may no longer have the virus. About half of those who are infected
with HPV are sexually active adolescents and young adults 15 to 24 years of age.5 Between 5% and 30% of individuals infected with HPV are infected with multiple types of HPV.
Each year, about 6.2 million people in the U.S. become newly infected.1
Estimates for the incidence and prevalence of genital warts
caused by low-risk types of HPV are imprecise. About 1% of sexually active adults have visible genital warts at any point in time.
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